Duchenne muscular dystrophy (DMD) is the most common form of muscular dystrophy affecting 1 in 3,500 live born males in all races. It is caused by a mutation of a gene on the X chromosome, which provides the instruction for the production of the protein Dystrophin. This protein is located inside the muscle cell membrane. When it is absent the muscle cells collapse and die and Duchenne muscular dystrophy develops. Symptoms of DMD usually appear between ages two and five years and may include difficulty: running, jumping, climbing, rising from the floor; frequent falls ,enlarged calf muscles toe walking and delays in language acquisition. The first muscles affected are those around the hips and upper thigh. Weakness gradually progresses to include all skeletal muscles, the muscles of respiration and the heart . Youths lose the ability to walk in late childhood/early adolescence and within a few short years upper body strength, respiratory and cardiac functions deteriorate. Our youths are frequently lost to us between late teens and mid 20's. But with your help, we will move these dreadful milestones further into each child's future. Duchenne Foundation has funded Australian Duchenne research, co-hosted three national conferences, disseminated online and multimedia educational materials, purchased life-saving medical equipment (cough assists, ventilators) and recreational equipment, (Easi-Standers, Beach Wheelchairs, Scooters) from grants, public campaigns, fundraisers and donations. Duchenne Foundation is a 100% voluntary organization.
PO Box 468 Smithfield, All Australia 4878 Australia